Neural integration of reward and effort
Determine how brain circuits represent and combine expected reward and effort costs to select actions, and how experience changes these computations.
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Determine how brain circuits represent and combine expected reward and effort costs to select actions, and how experience changes these computations.
Identify the molecular mechanisms that tag recently activated synapses and enable selective capture of products supporting persistent plasticity.
Explain how memories are physically encoded, maintained and retrieved across interacting synapses, cells and brain circuits.
Identify how neural representations of separate sensory features are combined into a coherent percept and distinguish competing mechanisms experimentally.
Infer the cellular, metabolic and genetic properties of the common ancestor of archaea and bacteria while accounting for horizontal transfer and subsequent gene loss.
Explain the evolutionary origin of the opposite glycerophosphate stereochemistry of archaeal and bacterial membranes and its implications for early cellular evolution.
Reconstruct how major viral lineages arose and their evolutionary relationships to cellular organisms and other replicating genetic elements.
Determine which selective mechanisms sustain sexual reproduction across populations despite its costs, and distinguish their contributions empirically.
Explain the emergence of codon–amino-acid assignments and the molecular coupling between nucleic-acid templates and peptide synthesis in early life.
Modeling the eye as a window on the body · Historical workshop question
Modeling the eye as a window on the body · Historical workshop question
Modeling the eye as a window on the body · Historical workshop question
Modeling the eye as a window on the body · Historical workshop question
Modeling the eye as a window on the body · Historical workshop question
Modeling the eye as a window on the body · Historical workshop question
Modeling the eye as a window on the body · Historical workshop question
Modeling the eye as a window on the body · Historical workshop question
Modeling the eye as a window on the body · Historical workshop question
Artificial Life, Biological Neural Networks, and Biological Rhythms · ICM 2002: Rhythms of the Nervous System Mathematical Themes and Variations
Biophysics and Biomechanics · ICM 2006: Cardiovascular mathematics
Population Dynamics, Epidemiology, and Ecology · ICM 2022: Multiscale eco-evolutionary models from individuals to populations
Genetics, Genomics, and Evolution · ICM 2022: Multiscale eco-evolutionary models from individuals to populations
Population Dynamics, Epidemiology, and Ecology · ICM 2022: Multiscale eco-evolutionary models from individuals to populations
Biophysics and Biomechanics · ICM 2006: Cardiovascular mathematics
Biophysics and Biomechanics · ICM 2006: Cardiovascular mathematics